More predictive in vitro assays may improve nanomedicine

Feb 01, 2022 (Nanowerk News) Messenger RNA (mRNA) vaccines are a prime example of the promising field of nanomedicine. But progress in the design and application of nanoparticles as efficient delivery vehicles for biopharmaceutics containing nucleic acid or protein drug substances is, unfortunately, remarkably slow. One recent obstacle to drug...

Novel nanoparticle SARS-CoV-2 vaccine combines immune focusing and self-assembling nanoparticles to elicit more potent protection

Feb 01, 2022 (Nanowerk News) The first generation of COVID-19 vaccines have been highly effective, but also have limitations: their efficacy can wane without a booster shot, and they may be less effective against some variants. Now scientists at The Wistar Institute have developed a more targeted vaccine that, in...

Engineering a multi-element atomic arrangement

Feb 01, 2022 (Nanowerk News) For the first time, a research group at the University of Maryland (UMD) has demonstrated the single phase nanoscale multi-principal element intermetallics (MPEIs) with up to 8 different metals – completely devoid of particle growth, or phase separation - via a novel multi-element disorder-to-order strategy....