Distinguishing between right and left with magnets

Jan 18, 2023 (Nanowerk News) Chirality control of molecules and crystals is critical to multiple fields of research such as drug development and display device research. In recent years, new attempts have been made to take advantage of magnets to separate handedness (left or right) of chiral molecules in a...

The effects of tightening a molecular knot

Jan 18, 2023 (Nanowerk News) A study conducted by Anne-Sophie Duwez and Damien Sluysmans from the NANOCHEM group at the University of Liège has made it possible to decode the mechanical response of small-molecule synthetic overhand knots by single-molecule pulling experiments. The results, published in the journal Chem ("Mechanical tightening...

Modified CRISPR-based enzymes improve the prospect of inserting entire genes into the genome to overcome disease-causing mutations

Jan 18, 2023 (Nanowerk News) Many genetic diseases are caused by diverse mutations spread across an entire gene, and designing genome editing approaches for each patient’s mutation would be impractical and costly. Investigators at Massachusetts General Hospital (MGH) recently developed an optimized method that improves the accuracy of inserting large...