Broad-spectrum inhibition of inflammasome activation by inorganic nanomaterials

Jul 24, 2023 (Nanowerk News) Excessive activation of inflammasomes is associated with various diseases, including gout, Alzheimer's disease, atherosclerosis, and type 2 diabetes. Given the pivotal role of macrophages in both inflammasome activation and nanoparticle phagocytosis, the discovery of anti-inflammatory nanoparticles specifically targeting macrophages could more effectively modulated inflammatory response...