Harnessing the power of the biomolecular corona to advance lipid nanoparticle therapeutics

Mar 14, 2024 (Nanowerk Spotlight) Lipid nanoparticles (LNPs) have garnered widespread attention following their successful application in delivering mRNA vaccines during the COVID-19 pandemic. However, to fully realize their potential for diverse therapeutic applications, scientists must overcome several clinical hurdles. In a recent forum published in Trends in Biotechnology ("Precise...

Nanocarrier with escape reflex

Mar 14, 2024 (Nanowerk News) Protein-based drugs must be transported into cells in a way that prevents their immediate degradation. A new approach is intended to ensure that they remain intact only in certain cells, such as cancer cells. In the journal Angewandte Chemie ("Selective Intracellular Delivery of Antibodies in...

Innovative nanoparticle therapy offers new hope for burn victims

Mar 14, 2024 (Nanowerk News) Scientists have developed a new nanoparticle treatment that significantly improves outcomes for severe burn-induced intestinal barrier disruption. The study introduces Luminol-conjugated cyclodextrin (LCD) nanoparticles, offering a promising therapeutic intervention for one of the most critical complications following severe burn injuries. Severe burns can cause critical...

Researchers overcome lattice mismatch issue to advance optoelectronic applications

Mar 14, 2024 (Nanowerk News) A research team from City University of Hong Kong (CityU) recently successfully achieved lattice-mismatch-free construction of III-V/chalcogenide core-shell heterostructure nanowires for electronic and optoelectronic applications. This breakthrough addresses crucial technological challenges related to the lattice mismatch problem in the growth of high-quality heterostructure semiconductors, leading...

Quantum dance to the beat of a drum

Mar 14, 2024 (Nanowerk News) Throwing a ball into the air, one can transfer arbitrary energy to the ball such that it flies higher or lower. One of the oddities of quantum physics is that particles, e.g., electrons, can often only take on quantized energy values – as if the...